Honey Shows Promise as a Weapon Against Diabetic Foot Ulcers: Study Review

Diabetic foot ulcers (DFUs) are a serious complication for people with diabetes, often leading to amputations. With the growing number of diabetes cases, the risk of DFUs is also rising. These chronic wounds become breeding grounds for bacteria, some resistant to antibiotics, making treatment challenging.

A review suggests honey may offer a safe, effective, and affordable weapon in the fight against DFUs. Researchers explored the potential of honey in wound healing, particularly for diabetic foot ulcers.

Why Honey?

Honey boasts several properties that make it a potential weapon against DFUs:

  • Antibacterial Power: Honey has been shown to be effective against various bacteria, including multidrug-resistant strains.
  • Wound Healing Properties: Honey’s physical and chemical characteristics, including its low pH, high sugar content, and presence of hydrogen peroxide, promote anti-inflammatory and antioxidant activity, aiding wound healing.

Reviewing the Evidence

The review examined studies on how honey promotes wound healing in animal models and humans with DFUs. The findings were encouraging:

  • Faster Healing: Many studies reported accelerated wound healing and contraction in patients treated with honey.
  • Reduced Amputation Rates: Studies suggested a potential decrease in amputations and hospital stays with honey treatment.

Challenges and Future Directions

A key limitation identified in the review was the lack of detailed information about the specific type of honey used in many studies. Different honeys have varying physical and chemical properties, potentially impacting their effectiveness.

Further research is needed to:

  • Compare Different Honey Types: Investigate how the unique properties of different honeys influence wound healing.
  • Standardize Honey Use: Develop standardized protocols for using honey in DFU treatment.

Honey: A Promising Option for DFU Management

Despite limitations, this review highlights honey’s potential as a cost-effective and safe option for managing DFUs. As research progresses, honey could become a valuable tool in the fight against this serious diabetic complication.

Andrea Bezerra, Hélder Fonseca, Francisca Rodrigues, Cristina Delerue-Matos, Irene Gouvinhas, and Juliana Garcia. Honey Therapy in Diabetic Foot Ulcers: A Promising Strategy for Effective Wound Healing. Appl. Sci. 2023, 13(23), 12820;

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